Dr. Pamela Keel is Distinguished Research Professor of Psychology at Florida State University. Dr. Keel has served as president of the Academy of Eating Disorders and the Eating Disorder Research Society and has contributed widely to the field of eating disorders. Here we discuss how Dr. Keel’s work on purging disorder stemmed from her earlier clinical work on bulimia nervosa and how our existing diagnostic system fails to describe the syndrome of purging that burdens a significant number of individuals.